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Latanoprostene bunod

CAS No. 860005-21-6

Latanoprostene bunod ( NCX116; LBN )

Catalog No. M24854 CAS No. 860005-21-6

Latanoprostene bunod is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Latanoprostene bunod
  • Note
    Research use only, not for human use.
  • Brief Description
    Latanoprostene bunod is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic.
  • Description
    Latanoprostene bunod is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic. It is used for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT).
  • Synonyms
    NCX116; LBN
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    860005-21-6
  • Formula Weight
    507.6
  • Molecular Formula
    C27H41NO8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (197.00 mM; Need ultrasonic)
  • SMILES
    C1[C@H]([C@@H]([C@H]([C@H]1O)C/C=C\CCCC(=O)OCCCCO[N+](=O)[O-])CC[C@H](CCC2=CC=CC=C2)O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Cavet ME, et al. The Role of Nitric Oxide in the Intraocular Pressure Lowering Efficacy of Latanoprostene Bunod: Review of Nonclinical Studies. J Ocul Pharmacol Ther. 2018 Jan/Feb;34(1-2):52-60.
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